Small particle formation

C - Chemistry – Metallurgy – 07 – C

Patent

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260/119, 260/263

C07C 59/52 (2006.01) A61K 9/16 (2006.01) B01J 13/10 (2006.01) C07D 239/42 (2006.01)

Patent

CA 1245631

ABSTRACT The present invention is concerned with the formation of small particles of organic compounds whose solubility in water is independent of temperature and greater at a first pH than at a second pH, upon precipitation by pH change with or without a change in temperature, but in the presence of a surfactant mixture.

457113

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