Small spherical particles of low molecular weight organic...

Details Small spherical particles of low molecular weight organic... Small spherical particles of low molecular weight organic...

A - Human Necessities

61

K

A61K 9/14 (2006.01) A01N 25/12 (2006.01) A61K 8/02 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01) B01J 2/00 (2006.01)

Patent

CA 2532874

The invention provides homogeneous small spherical particles of low molecular weight organic molecules, said small spherical particles having a uniform shape, a narrow size distribution and average diameter of 0.01-200 ~m. The invention further provides methods of preparation and methods of use of the small spherical particles. These small spherical particles are suitable for applications that require delivery of micron-size or nanosized particles with uniform size and good aerodynamic or flow characteristics. Pulmonary, intravenous, and other means of administration are among the delivery routes that may benefit from these small spherical particles.

La présente invention concerne de petites particules sphériques homogènes de molécules organiques de faible poids moléculaire, lesquelles petites particules sphériques présentent une forme uniforme, une distribution granulométrique étroite et un diamètre moyen compris entre 0,01 et 200 µm. Cette invention concerne également des procédés de préparation et des procédés d'utilisation de ces petites particules sphériques. Ces petites particules sphériques conviennent à des applications qui requièrent l'administration de particules de taille micrométrique ou nanométrique présentant des dimensions uniformes ainsi que de bonnes caractéristiques aérodynamiques ou d'écoulement. Des modes d'administration par voie pulmonaire, intraveineuse ou autres figurent parmi les voies d'administration qui peuvent bénéficier de ces petites particules sphériques.

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