Smallpox monoclonal antibody

Details Smallpox monoclonal antibody Smallpox monoclonal antibody

A - Human Necessities

61

K

A61K 39/42 (2006.01) C07K 16/08 (2006.01) C07K 16/46 (2006.01) C12N 5/16 (2006.01) C12N 15/13 (2006.01) C12P 21/08 (2006.01) C07K 14/07 (2006.01)

Patent

CA 2661659

Humanized monoclonal antibodies against the vaccinia virus B5R surface antigen. The antibodies are effective in treating smallpox infection. Also disclosed are nucleic acids that encode the heavy and light chains of such antibodies and cells that express them.

L'invention concerne des anticorps monoclonaux humanisés contre l'antigène de surface B5R du virus de la vaccine. Les anticorps sont efficaces pour traiter la variole. Sont également décrits des acides nucléiques qui codent les chaînes lourdes et légères de tels anticorps et les cellules qui les expriment.

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