C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/475 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2089111
A recombinant non-glycosylated mammalian growth factor (BTC-GF) stimulates proliferation of human smooth muscle cells. Especially, the amino acid sequence of the protein deduced from the nucleotide sequence coding for human BTC-GF is as that comprising the amino acids No. 1 to No. 147 of Figure 10 or the amino acids No. 1 to 80 of Figure 10, and the amino acid sequence of the protein deduced from the nucleotide sequence coding far mouse BTC-GF is as that comprising the amino acids No. 1 to No. 146 of Figure 9.
Folkman Moses J.
Igarashi Koichi
Shing Yuen
Children's Medical Center Corporation
Fetherstonhaugh & Co.
Takeda Chemical Industries Ltd.
Takeda Pharmaceutical Company Limited
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