Smooth muscle spasmolytic agents, compositions and methods...

Details Smooth muscle spasmolytic agents, compositions and methods... Smooth muscle spasmolytic agents, compositions and methods...

C - Chemistry, Metallurgy

07

C

C07C 235/34 (2006.01) A61K 31/135 (2006.01) A61K 31/16 (2006.01) A61K 31/216 (2006.01) A61K 31/22 (2006.01) A61K 31/65 (2006.01) C07C 219/20 (2006.01) C07C 225/14 (2006.01) C07C 225/18 (2006.01)

Patent

CA 2259316

Disclosed are racemates and optically active isomers of substituted aminobutyl derivatives of cyclohexylphenylglycolic acid, including esters, amides and keto isosteres, which possess smooth muscle spaxmolytic properties with reduced anticholinergic and cardiodepressive side effects.

La présente invention concerne des composés racémiques et des isomères optiquement actives de dérivés aminobutyl substitués de l'acide cyclohexylphénylglycolique, incluant des esters des amides et des kéto-isostères. Ces composés et isomères sont dotés de propriétés spasmolytiques sur la musculature lisse, tout en présentant des effets secondaires anticholinergiques et cardiodépresseurs réduits.

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