C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/04 (2006.01)
Patent
CA 2612296
Provided are methods for the synthesis of heterocyclic compounds such as benzimidazole carboxylic acid core structures having Formula Ia-2 and their synthetic intermediates: wherein X1, X2, X5, R1, R2 and R4 are as defined herein. Compounds of Formula Ia-2 and their synthetic intermediates can be used to prepare heterocyclic derivatives such as benzimidazole derivatives.
L'invention concerne des procédés pour la synthèse de composés hétérocycliques tels que des structures centrales d'acide carboxylique de benzimidazole ayant la formule Ia-2 ainsi que leurs intermédiaires synthétiques, dans laquelle X1, X2, X5, R1, R2 et R4 sont tels que définis dans le descriptif. Des composés de la Formule Ia-2 et leurs intermédiaires synthétiques peuvent servir dans la préparation de dérivés hétérocycliques, tels que des dérivés de benzimidazole.
Barnett Bradley R.
Demattei John
Evans Matthew Charles
Ford James Gair
Hache Bruno P.
Array Biopharma Inc.
Astrazeneca Ab
Gowling Lafleur Henderson Llp
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