Snurportin i human m3g-cap specific nucleus import receptor...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2333895

The invention relates to a novel polypeptide or a functional variant thereof, acting as a 5'-2,2,7 terminal trymethylguanosine(m3G-)Cap-specific receptor of nucleus import in cells, to the production and to the use thereof. The invention is preferably used as a medicament or diagnostic reagent.

L'invention concerne un nouveau polypeptide ou une variante fonctionnelle de celui-ci, lequel agit dans les cellules comme un récepteur d'importation de noyau spécifique de la triméthylguanosine (m¿3?G-)Cap à terminaison 5'-2,2,7, sa préparation et son utilisation. L'invention s'utilise de préférence comme médicament ou agent diagnostique.

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