Sodium channel blockers

Details Sodium channel blockers Sodium channel blockers

C - Chemistry, Metallurgy

07

D

C07D 241/28 (2006.01) A61K 31/4965 (2006.01) A61P 7/10 (2006.01) C07D 241/24 (2006.01) C07D 241/26 (2006.01)

Patent

CA 2476430

The invention is directed to sodium channel blockers consisting of pyrazinoylguanidine compounds of the formula (I): (see formula I) These compounds give a prolonged pharmacodynamic half-life on mucosal surfaces and make them particularly useful for treating cardiovascular disease.

L'invention concerne des bloqueurs de canaux sodium ainsi qu'une pluralité de méthodes de traitement utilisant lesdits bloqueurs de canaux de sodium de l'invention.

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