Sodium-hydrogen exchanger type 1 inhibitor crystals

Details Sodium-hydrogen exchanger type 1 inhibitor crystals Sodium-hydrogen exchanger type 1 inhibitor crystals

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/4709 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2389020

NHE-1 inhibitor crystal of Formula (I), methods of using such NHE-1 inhibitor crystal and pharmaceutical compositions containing such NHE-1 inhibitor crystal. The NHE-1 inhibitor crystal is useful for the reduction of tissue damage resulting from tissue ischemia.

L'invention concerne des cristaux d'inhibiteurs de l'échangeur sodium-hydrogène de type 1 (NHE-1), les méthodes d'utilisation desdits cristaux d'inhibiteurs NHE-1, et des compositions pharmaceutiques renfermant les cristaux d'inhibiteurs NHE-1. Ces cristaux d'inhibiteurs NHE-1 sont utilisés pour limiter les lésions tissulaires résultant de l'ischémie tissulaire.

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