Sodium salt of...

Details Sodium salt of... Sodium salt of...

C - Chemistry, Metallurgy

07

C

C07C 381/02 (2006.01) A61K 31/185 (2006.01)

Patent

CA 2269089

Sodium salt of [poly-2.5-dihydroxy-phenylene)1-4-thiosulfonic acid, (see above formula) where n = 0 ÷ 4, being a cyclo-linear polymer, is proposed as the regulator of a cell metabolism. There are provided for the production of the claimed preparation: interaction of para-benzoquinone and sodium thiosulfate at the molar ratio of 10:1 to 2:1, separation of a final product, and purification from admixtures. The interaction of para-benzoquinone and sodium thiosulfate is made in a water-organic medium, preferably in the water-acetone one, at the temperature of 40 to 70 °C.

On propose l'utilisation, en tant que régulateur du métabolisme cellulaire, du sel de sodium de l'acide [poly-(2,5-dihydroxy-phénylène)]-4-thiosulfonique, lequel est un polymère cyclo-linéaire. On décrit le procédé de production de la préparation revendiquée, lequel consiste à faire réagir une para-benzoquinone avec un thiosulfate de sodium selon un rapport molaire compris entre 10:1 et 2:1, à séparer le produit final et à purifier celui-ci des mélanges additionnels. On exécute la réaction entre la para-benzoquinone et le thiosulfate de sodium dans un milieu organique aqueux, de préférence dans un milieu eau-acétone, à une température comprise entre 40 et 70 DEG C.

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