A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/106 (2006.01) C12N 1/21 (2006.01) C12N 15/31 (2006.01)
Patent
CA 2179420
V. cholerae vaccine strains which have a soft agar penetration-defective phenotype and methods for making such strains are described. Also described are methods for identifying new genes involve in V. cholerae motility and the cloning, identification, and sequencing of V. cholerae motB and fliC genes.
La présente invention concerne des souches vaccinales du vibrio cholerae à phénotype atténué caractérisé par une défaillance à la pénétration dans l'agar, et les procédés de fabrication de ces souches. L'invention concerne également des procédés d'identification de nouveaux gènes concernés par la motilité du vibrio cholerae, et des procédés de clonage, d'identification et de séquençage des gènes motB et fliC du vibrio cholerae.
Beattie David T.
Camilli Andrew
Gardel Claudette L.
Mekalanos John J.
Celldex Therapeutics Inc.
President And Fellows Of Harvard College
Smart & Biggar
Virus Research Institute
LandOfFree
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