Soft capsules comprising palonosetron hydrochloride having...

A - Human Necessities – 61 – K

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A61K 9/48 (2006.01) A61K 9/66 (2006.01) A61K 31/473 (2006.01)

Patent

CA 2666512

Provided are solid oral dosage forms of palonosetron hydrochloride, methods of using the dosage forms to treat emesis, and methods of making the dosage forms. The dosage forms have improved stability and bioavailability, and are preferably in the form of liquid filled capsules.

L'invention porte sur des formes posologiques orales solides de chlorhydrate de palonosétron, sur des procédés d'utilisation des formes posologiques pour traiter un vomissement, et sur des procédés de fabrication des formes posologiques. Les formes posologiques ont une stabilité et une biodisponibilité améliorées et sont, de préférence, sous la forme de capsules remplies de liquide.

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