Soft contact lens wetting solution and in-eye comfort...

C - Chemistry – Metallurgy – 11 – D

Patent

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C11D 3/48 (2006.01) A61K 9/08 (2006.01) A61K 31/045 (2006.01) A61K 31/505 (2006.01) C08L 71/02 (2006.01) C11D 7/32 (2006.01) G02C 7/04 (2006.01) G02C 13/00 (2006.01)

Patent

CA 1256776

SOFT CONTACT LENS WETTING SOLUTION AND IN-EYE COMFORT SOLUTION CONTAINING PRESERVATIVE AND METHOD ABSTRACT Aqueous compositions for the wetting and re-wetting of contact lenses and especially silicone, silicone copolymer (gas-permeable) and soft contact lenses are provided that include a preservative system. The preservative system includes trimethoprim, and benzyl alcohol as an adjuvant bactericide and optionally a salt of EDTA. The use of preservatives which are known to cause eye irritation and lens discoloration such as thimerosal, sorbic acid, potassium chloride and chlorhexidine is eliminated. Wetting and re-wetting compositions which incorporate the preservative system and include thickening and wetting agents are also provided. The wetting and re-wetting solutions can be instilled directly into the eye during contact lens wear- ing periods and are especially useful for wetting silicone, silicone copolymer and soft daily and extended wear contact lenses.

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