Softgel-compatible composition containing retinol

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/16 (2006.01) A61K 9/48 (2006.01) A61K 9/50 (2006.01) A61K 31/07 (2006.01) A61K 31/375 (2006.01)

Patent

CA 2328945

A softgel-compatible composition containing retinol comprises retinol- impregnated microparticles. The composition may include an optionally thickened silicone oil, or may include an emulsion comprising a silicone oil. Ascorbic acid may be present as ascorbic acid-impregnated microparticles and/or within the emulsion. Such compositions are compatible with softgels, and may also be used in other dispensing containers, such as sachets, tubes, and airless pumps.

L'invention concerne une composition compatible avec un gel mou contenant du rétinol et des microparticules imprégnées de rétinol. La composition peut comprendre une huile de silicone éventuellement épaissie ou une émulsion renfermant une huile de silicone. Un acide ascorbique peut être présent sous forme de microparticules imprégnées d'acide ascorbique et/ou dans l'émulsion. Des telles compositions sont compatibles avec des gels mous et peuvent être utilisées dans d'autres récipients de distribution tels que des sachets, des tubes ou des pompes à dépression.

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