Software assisted methods for probing the biochemical basis...

G - Physics – 06 – F

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G06F 19/12 (2011.01)

Patent

CA 2700558

The present invention relates to computational methods, systems and apparatus useful in the identification of similarities and/or differences between a plurality of biological states, such as altered biological states in an animal (e.g., a mammal or human). Particularly, the invention relates to comparing two or more causal system models ("CSMs") which each are indicative of a biological state, such as a disease state, a toxic state, or a drug-or therapy- induced state. The present invention also relates to generating a general CSM from a comparison of two or more other CSMs, and subsequently comparing one or more of the other CSMs to the general CSM. Either of these techniques, or a combination of the two techniques, can be used to identify unique and common features in each CSM.

La présente invention a pour objet des procédés, systèmes et appareils de calcul utiles pour identifier des similarités et/ou différences entre une pluralité d'états biologiques, tels que des états biologiques altérés chez un animal (par ex : un mammifère ou un humain). En particulier, l'invention concerne la comparaison de deux modèles de système causal (CSM) ou plus, qui indiquent chacun un état biologique, tel qu'un état maladif, un état toxique ou un état induit par un médicament ou une thérapie. La présente invention concerne également la génération d'un CSM général à partir d'une comparaison de deux autres CSM ou plus, puis la comparaison d'un ou de plusieurs autres CSM avec le CSM général. Chacune de ces techniques, ou une combinaison des deux techniques, peut être utilisée pour identifier des caractéristiques uniques et communes dans chaque CSM.

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