Sol-gel biosensors

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/00 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2506513

Method of Producing Sol-gels and Sol-gel Biosensors. The invention discloses a method of producing a layer of sol-gel on a substrate comprising the steps of: (a) providing a acidified sol suspension; (b) at least partially neutralising the acidified sol suspension to form a neutralised sol suspension; (c) contacting an electrically conductive surface with the neutralised sol suspension; and (d) applying an electrical potential to the electrically conductive surface to cause a layer of sol-gel to form on the surface of the electrically conductive surface. Preferably, the neutralised sol-gel has a biological material, such as an enzyme added. Biosensors obtained by using the method are also provided.

L'invention se rapporte à un procédé de production d'une couche de revêtement sol-gel sur un substrat comprenant les étapes suivantes : (a) se munir d'une suspension sol acidifiée ; (b) neutraliser au moins partiellement la suspension sol acidifiée pour former une suspension sol neutralisée ; (c) mettre en contact une surface électriquement conductrice avec la suspension sol neutralisée et (d) appliquer un potentiel électrique à la surface électriquement conductrice de manière à provoquer la formation d'une couche de revêtement sol-gel sur la surface électriquement conductrice. De préférence, la solution sol-gel neutralisée est additionnée d'une matière biologique, telle qu'une enzyme. L'invention se rapporte également à des biocapteurs obtenus selon le procédé ci-dessus.

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