Sol-gel encapsulated enzyme

Details Sol-gel encapsulated enzyme Sol-gel encapsulated enzyme

C - Chemistry, Metallurgy

12

N

C12N 11/14 (2006.01) C03C 4/00 (2006.01) C03C 14/00 (2006.01) C12N 9/96 (2006.01) C12Q 1/00 (2006.01) G01N 33/543 (2006.01) G01N 33/552 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2115671

An active biological material encapsulated in a glass is formed using a sol-gel process. A metal alkoxide is mixed with water (12) and exposed to ultrasonic energy at pH <= 2 to form a single phase solution which is then buffered to a pH between about 5 and 7 (17). The buffered solution is then mixed with the active biological material (20) and the resultant gel (21) is aged (22) and dried (24). The dried product is a transparent po- rous glass with substantially all of the added active biological material encapsulated therein (26), the biological material re- taining a high level of activity.

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