Solid, at least two-phase formulations of an opioid...

Details Solid, at least two-phase formulations of an opioid... Solid, at least two-phase formulations of an opioid...

A - Human Necessities

61

K

A61K 31/485 (2006.01) A61J 3/06 (2006.01) A61K 9/22 (2006.01) A61K 9/24 (2006.01)

Patent

CA 2229621

A solid, at least two-phase formulation of at least one opioid analgesic in a matrix, where each of the two phases contains at least one opioid with an in vitro release rate by the Ph.Eur. paddle method of more than 50% by weight of active ingredient after one hour.

Formulation solide, à au moins deux phases, d'au moins un analgésique opioïde dans une matrice, dans laquelle chacune des deux phases contient au moins un opioïde avec un taux de libération in vitro, selon la méthode de dissolution par un agitateur à ailettes de la Ph. Eur., de plus de 50 % en poids du principe actif après une heure.

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