A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/14 (2006.01) A61K 9/22 (2006.01)
Patent
CA 2197982
The present invention encompasses solid dose delivery systems for administration of guest substances. Preferred delivery systems are suitable for delivery of bioactive materials to subcutaneous and intradermal, intramuscular, intravenous tissue, the delivery system being sized and shaped for penetrating the epidermis. The delivery systems comprise a vitreous vehicle loaded with the guest substance and capable of releasing the guest substance in situ at various controlled rates. The present invention further includes methods of making and using the solid dose delivery systems.
Cette invention se rapporte à des systèmes d'apport de doses de substances solides, qui servent à l'administration de substances hôtes incorporées dans ces doses. Les systèmes d'administration préférés de cette invention se prêtent à l'apport de matières bioactives dans des tissus intraveineux, intramusculaires, sous-cutanés et intradermiques, la taille et la forme de ce système d'apport étant conçues pour lui permettre de pénétrer dans l'épiderme. Ces systèmes d'apport comprennent un excipient vitreux chargé de la substance hôte et capable de libérer cette substance hôte in situ à divers taux contrôlés. Cette invention se rapporte en outre à des procédés pour fabriquer et utiliser ces systèmes d'administration de doses de substances solides.
Blair Julian Alexander
Colaco Camilo
Duffy John Alistair
Jerrow Mohammad Abdel Zahra
Kampinga Jaap
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Quadrant Drug Delivery Limited
Quadrant Holdings Cambridge Limited
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