A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/11 (2006.01) A61J 3/10 (2006.01) A61K 9/20 (2006.01) A61K 47/26 (2006.01)
Patent
CA 2486833
The present invention relates to a novel pharmaceutical composition as a solid dosage farm comprising desmopressin as a therapeutically active ingredient, and to a method for manufacturing thereof. The invention relates to a pharmaceutical composition as a solid dosage form comprising desmopressin, or a pharmaceutically acceptable salt thereof, as a therapeutically active ingredient together with a pharmaceutically acceptable excipient, diluent or carrier, or mixture thereof, wherein at least one of said excipient, diluent and carrier is a disaccharide, wherein the disaccharide has an average particle size in the range of from 70 to 500 µm. A method according to the present invention provides an improved production of solid dosage forms of desmopressin.
L'invention concerne une nouvelle composition pharmaceutique comme forme posologique solide comprenant la desmopressine comme principe thérapeutiquement actif, et un procédé de fabrication associé. L'invention concerne une composition pharmaceutique comme forme posologique solide comprenant la desmopressine, ou un sel pharmaceutiquement acceptable de celle-ci, comme principe thérapeutiquement actif ainsi qu'un excipient, diluant ou support, ou un mélange de ceux-ci pharmaceutiquement acceptable. Au moins un excipient, un diluant ou un support est une substance choisie entre un monosaccharide, un disaccharide, un oligosaccharide et un polysaccharide, dont la taille particulaire moyenne est comprise entre 60 et 1000 mu m. L'invention concerne en outre un procédé de production améliorée de formes posologiques solides de la desmopressine.
Lomryd Hakan
Nicklasson Helena
Olsson Lars-Erik
Ferring B.v.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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