Solid dosage form with a film containing an active...

A - Human Necessities – 61 – K

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Details

A61K 9/20 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2667724

The present invention relates to a solid dosage form with at least one film (1), which contains an active substance at least in sections. The dosage form is characterized in that the concentration of active substance in film (1) or in the films has a gradient in a direction normal to the thickness of film (1). The invention further relates to a method of production of a solid dosage form with an active substance, in which at least one film (1) is produced, which contains an active substance at least in sections, with the concentration of active substance in film (1) or in the films having a gradient in the longitudinal direction of the film. This film is then formed to produce the dosage form.

Cette invention concerne une forme pharmaceutique solide comportant au moins une pellicule (1), qui renferme une substance active au moins en sections. La forme pharmaceutique se caractérise en ce que la concentration de la substance active dans la pellicule (1) ou dans les pellicules a un gradient dans une direction normale à l'épaisseur du film (1). Cette invention concerne également un procédé de production d'une forme pharmaceutique solide contenant une substance active, dans lequel au moins un film (1) est produit ; ledit film contient une substance active au moins en sections, la concentration de la substance active dans le film (1) ou dans les films ayant un gradient dans la direction longitudinale du film. Ce film est ainsi formé pour produire la forme pharmaceutique.

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