Solid dosage forms comprising an enteric coating with...

A - Human Necessities – 61 – K

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A61K 9/50 (2006.01)

Patent

CA 2687130

The present invention refers to a solid dosage form comprising an inner coating located between a core containing a pharmaceutically active ingredient and an outer enteric coating; wherein said inner coating comprises a partially neutralized anionic polymeric material, and at least a carboxylic acid having 2 to 16 carbon atoms the salts thereof or mixtures of said acid and its salt; wherein said outer coating comprises an anionic polymeric material which is less or not at all neutralized than the material of the inner coating.

La présente invention concerne une forme posologique solide comprenant un revêtement intérieur situé entre un cAEur contenant un ingrédient pharmaceutiquement actif et un revêtement gastrorésistant extérieur ; ledit revêtement intérieur comprenant une substance polymère anionique partiellement neutralisée, et au moins un acide carboxylique ayant de 2 à 16 atomes de carbone, les sels de celui-ci ou les mélanges dudit acide et de ses sels ; ledit revêtement extérieur comprenant une substance polymère anionique qui est moins ou pas du tout neutralisée par rapport à la substance du revêtement intérieur.

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