Solid drug forms obtainable by extrusion of an...

Details Solid drug forms obtainable by extrusion of an... Solid drug forms obtainable by extrusion of an...

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61J 3/06 (2006.01) A61K 31/275 (2006.01) A61K 31/277 (2006.01) A61K 47/34 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2230950

The invention concerns solid medicaments obtained by extrusion with subsequent shaping of a solvent-free melt, containing in addition to one or a plurality of active substances: A) between 10 and 90 wt.% of a thermoplastically processable water-soluble polymer, B) between and 85 wt.% isomalt; and C) between 0 and 5 wt.% lecithin, the total of all the contents equalling 100 wt.%.

L'invention concerne des formes médicamenteuses solides que l'on peut obtenir par extrusion avec formage consécutif d'une masse fondue dépourvue de solvants et contenant, outre au moins une substance active, : A) de 10 à 90 % en poids d'un polymère soluble dans l'eau et thermoplastiquement transformable , B) de 5 à 85 % en poids d'isomalt et C) de 0 à 5 % en poids de lécithine, la somme de l'ensemble de ces composants devant être égale à 100 % en poids.

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