Solid forms comprising (-)-o-desmethylvenlafaxine and uses...

C - Chemistry – Metallurgy – 07 – C

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C07C 215/64 (2006.01) A61K 31/137 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2678599

Solid forms comprising a compound useful in the treatment, prevention and management of various conditions and diseases are provided herein. In particular, the invention provides solid forms comprising (-)-O-desmethylvenlafaxine, including salts thereof, having utility for the treatment, prevention and management of conditions and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.

La présente invention concerne des formes solides comprenant un composé utile au traitement, à la prévention et à la gestion de diverses conditions et maladies. En particulier, la présente invention concerne des formes solides comprenant du (-)-O-desméthylvenlafaxine, comportant des sels de celui-ci, ayant une utilité pour le traitement, la prévention et la gestion de conditions et de troubles comportant, sans y être limités, des troubles affectifs tels que la dépression, des troubles bipolaire et maniaque, un trouble du défaut d'attention, un trouble du défaut d'attention avec de l'hyperactivité, la maladie de Parkinson, l'épilepsie, des troubles de la fonction cérébrale, l'obésité et le gain de poids, l'incontinence, des troubles de démence et liés à celle-ci.

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