C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/12 (2006.01) A61K 31/443 (2006.01) A61P 11/00 (2006.01)
Patent
CA 2706920
The present invention relates to a substantially crystalline and free solid state form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclo-propanecarboxamido)-3- methylPyridin-2-yl)benzoic acid (Form I) of following formula: (I), pharmaceutical compositions thereof, and methods of treatment therewith.
L'invention concerne une forme sensiblement cristalline et à l'état libre solide d'acide 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-méthylpyridin-2-yl)benzoïque (forme I) de formule suivante, des compositions pharmaceutiques la comprenant et des procédés de traitement avec cette dernière.
Keshavarz-Shokri Ali
Krawiec Mariusz
Zhang Beili
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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