C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2636954
The invention relates to new crystalline forms of {6-[4-{4-ethyl-piperazin-1 - ylmethyl)- phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-((R)-1-phenyl-ethyl)- amine, the process for the preparation of these crystalline forms of {6-[4-(4- ethyl-piperazin-1-ylmethyl)-phenyl]-7H- pyrrolo[2,3-d]pyrimidin-4-yl}-((R)-1 - phenyl-ethyl)-amine, compositions containing these crystalline forms of {6-[4- (4-ethyl-piperazin-1-ylmethyl)-phenyl]-7H-pyrrolo[2,3-d ]pyrimidin-4-yl}-((R)- 1-phenyl-ethyl)-amine, and the use of these crystalline forms of {6-[4-(4- ethyl- piperazin-1-ylmethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-{(R)-1- phenyl-ethyl)-amine in diagnostic methods or therapeutic treatment of warm- blooded animals, especially humans.
La présente invention concerne de nouvelles formes cristallines de la {6-[4-{4-éthyl-pipérazin-1-ylméthyl)phényl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-((R)-1-phényléthyl)amine. L~invention concerne également un procédé de préparation desdites formes cristallines et des compositions les contenant, ainsi que l~utilisation desdites formes cristallines dans la cadre de méthodes diagnostiques ou du traitement thérapeutique d~animaux à sang chaud, en particulier des êtres humains.
Fischer Reto
Mutz Michael
Fetherstonhaugh & Co.
Novartis Ag
LandOfFree
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