Solid forms of an anti-hiv phosphoindole compound

C - Chemistry – Metallurgy – 07 – F

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C07F 9/572 (2006.01) A61K 31/675 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2718608

Solid forms comprising a compound useful in the treatment, prevention and management of various conditions and diseases are provided herein. In particular, provided herein are solid forms comprising (2-carbamoyl-5-chloro-1H-indol-3-yl)-[3--((E)-2-cyano-vinyl)-5-methyl-phenyl]- (R)-phosphinic acid methyl ester, including salts thereof, having utility for the treatment, prevention and management of conditions and disorders including, but not limited to, human immunodeficiency virus infection.

La présente invention concerne des formes solides comprenant un composé utile dans le traitement, la prévention et le contrôle de différentes pathologies et maladies. En particulier, la présente invention concerne des formes solides comprenant lester méthylique dacide (2-carbamoyl-5-chloro-1H-indol-3-yl)-[3-((E)-2-cyano-vinyl)-5-méthyl-phényl]-(R)-phosphinique, y compris des sels de celui-ci, ayant une utilité pour le traitement, la prévention et le contrôle de pathologies et troubles comprenant, mais non limités à, linfection par le virus dimmunodéficience humaine.

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