Solid lipidic nanospheres suitable to a fast internalization...

A - Human Necessities – 61 – K

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Details

A61K 31/575 (2006.01) A61K 9/51 (2006.01) A61K 31/337 (2006.01) A61K 31/704 (2006.01) A61K 47/24 (2006.01) A61P 7/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2352149

The present invention relates to pharmaceutical compositions in form of solid lipidic nanospheres able to fast penetrate into the cells, comprising as an active substance a lipidic substance consisting of an ester of .alpha.-tocopherol or .delta.-tocopherol or of cholesterol or of glycerol with a carboxylic acid selected from acetic acid, propionic acid, butyric acid and succinic acid, useful in the treatment of tumoral pathologies and of Mediterranean anaemia.

L'invention porte sur des compositions pharmaceutiques sous forme de nanosphères solides de lipides pénétrant rapidement dans les cellules et dont le principe actif est une substance à base de lipides consistant en un ester d' alpha -tocophérol, ou de delta -tocophérol, ou de cholestérol, ou de glycérol, associé à un acide carboxylique choisi parmi les acides acétique, propionique, butyrique, et succinique. Lesdites compositions servent à traiter les pathologies tumorales et l'anémie méditerranéenne.

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