Solid medicinal preparation containing mannitol or lactose

Details Solid medicinal preparation containing mannitol or lactose Solid medicinal preparation containing mannitol or lactose

A - Human Necessities

61

K

A61K 31/4365 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2672134

A solid medicinal preparation containing the compound of the following general formula (I) or a pharmacologically acceptable salt thereof. It has improved content evenness. The solid medicinal preparation contains: (A) the compound of the following general formula (I): or a pharmacologically acceptable salt thereof; and (B) mannitol or lactose which, when examined under specific conditions, has a particle size distribution having a particle diameter at 90% cumulation of 80-300 µm.

L'invention concerne une préparation médicale sous forme solide contenant un composé de formule générale (I) ou un sel pharmacologiquement acceptable de celui-ci. Cette préparation sous forme solide présente une homogénéité améliorée en termes de contenu. Elle contient (A) le composé de formule générale (I) ou un sel pharmacologiquement acceptable de celui-ci, et (B) un mannitol ou un lactose qui, analysé dans des conditions spécifiques, présente une distribution granulométrique caractérisée par un diamètre des particules compris entre 80 et 300 µm à 90% d'accumulation.

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