Solid oral dosage form comprising a combination of metformin...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/64 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/48 (2006.01) A61K 31/155 (2006.01) A61P 3/10 (2006.01) A61P 5/50 (2006.01)

Patent

CA 2303537

The present invention relates to a solid oral dosage form comprising a combination of metformin and glibenclamide in which the size of glibenclamide is such that the glibenclamide bioavailability is comparable to the glibenclamide bioavailability obtained with a separate administration of metformin and glibenclamide.

L'invention concerne une forme posologique orale solide comprenant une combinaison de metformine et de glibenclamide, dans laquelle la taille du médicament glibenclamide est telle que la biodisponibilité de glibenclamide est comparable à une biodisponibilité de glibenclamide résultant de l'administration séparée de metformine et de glibenclamide.

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