Solid oral form of a medicinal preparation and a method for...

A - Human Necessities – 61 – K

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Details

A61K 9/20 (2006.01) A61J 3/00 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2645475

A solid oral form of an antibody-based medicinal preparation comprises an effective carrier quantity irrigated with an active form of an antibody aqueous-alcoholic dilution, which is prepared by combining a repeated successive antibody dilution with an external action, and pharmaceutically acceptable additives. The inventive method for producing a solid oral form of the antibody-based medicinal preparation consists in preparing an aqueous-alcoholic dilution of anti-substance antibodies, obtaining the active form by combining a repeated successive dilution and an external action according to a homeopathic process, irrigating a carrier with the thus obtained aqueous-alcoholic dilution in a pseudo-liquefied boiling layer, simultaneously drying said carrier at a temperature equal to or less than 35°C, mixing in a pharmaceutically acceptable sequence with pharmaceutically acceptable additives and in subsequently pelleting - forming pills by means of a direct dry pressing.

Cette invention concerne une forme orale solide d'une préparation médicinale à base d'anticorps comprenant une quantité efficace d'excipient arrosé d'une dilution hydroalcoolique d'anticorps sous forme active préparée par combinaison d'une dilution successive répétée d'anticorps avec une action externe et des additifs pharmaceutiquement acceptables. Le procédé de production d'une forme orale solide d'une préparation médicinale à base d'anticorps consiste à préparer une dilution hydroalcoolique d'anticorps dirigés contre une substance, à obtenir la forme active par combinaison d'une dilution successive répétée avec une action externe selon une méthode homéopathique, à arroser un excipient avec la dilution hydroalcoolique ainsi obtenue dans un lit d'ébullition pseudo-fluidisé tout en le faisant sécher à une température n'excédant pas 35°C, à le mélanger dans une succession pharmaceutiquement acceptable avec des additifs pharmaceutiquement acceptables puis à réaliser une granulation-formation de comprimés par moulage par compression à sec.

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