Solid oral forms of application containing ifosfamide as...

Details Solid oral forms of application containing ifosfamide as... Solid oral forms of application containing ifosfamide as...

A - Human Necessities

61

K

A61K 31/675 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2048367

Solid oral ifosfamide formulations are disclosed where the capsule mass substantially consists of the active substance ifosfamide and microcrystalline cellulase, or in the form of tablets which contain, in relation to one part by weight of ifosfamide, 0.1 - 1.0 parts by weight of tricalcium phosphate, and 0.04 - 0.4 parts by weight of polyethylene glycol as well as in addition, related to the weight of the tablet 5 - 60 % by weight of a filling and flow regulating agent, 1 - 10 % by weight of a disintegrant, 0.1 - 10 % by weight of an antiadhesion agent, and 0.1 - 80% by weight of a binding agent.

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