A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/5377 (2006.01)
Patent
CA 2624306
The invention concerns solid orally administerable 5-chlorine pharmaceutical dosage forms with rapid active principle release 5-chlorine-N-({(5S)-2-oxo-3- [4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophene carboxamide, which are in amorphous form and/or contain thermodynamically metastable crystal modification and have a rapid active principle release, and to methods for the production thereof, their use as medicaments, their use for the prophylaxis, secondary prophylaxis and/or treatment of diseases as well as to their use for producing a medicament for the prophylaxis, secondary prophylaxis and/or treatment of diseases.
L'invention concerne du 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phényl]-1,3-oxazolidine-5-yl}-méthyle)-2-thiophèncarboxamide solide, administré par voie orale et se présentant sous forme amorphe et/ou des formulations de présentation pharmaceutique contenant une modification des cristaux métastables de manière thermodynamique et présentant une libération des agents actifs rapide. L'invention concerne également des procédés de production desdites formulations, leur utilisation en tant que médicament, leur utilisation dans la prophylaxie, la prophylaxie secondaire et/ou le traitement de maladies, et leur utilisation dans la production d'un médicament destiné à la prophylaxie, à la prophylaxie secondaire et/ou au traitement de maladies.
Bayer Healthcare Ag
Bayer Schering Pharma Aktiengesellschaft
Fetherstonhaugh & Co.
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