Solid pharmaceutical composition comprising amlodipine and...

Details Solid pharmaceutical composition comprising amlodipine and... Solid pharmaceutical composition comprising amlodipine and...

A - Human Necessities

61

K

A61K 31/44 (2006.01)

Patent

CA 2749903

The present invention relates to a solid pharmaceutical composition for preventing or treating cardiovascular disorders comprising amlodipine or a pharmaceutically acceptable salt thereof and losartan or a pharmaceutically acceptable salt thereof, which exhibits high dissolution rates of amlodipine and losartan even under a low pH condition and improved storage stability.

La présente invention porte sur une composition pharmaceutique solide destinée à prévenir ou à traiter les troubles cardiovasculaires, comprenant de l'amlodipine ou un sel pharmaceutiquement acceptable de celle-ci et du losartan ou un sel pharmaceutiquement acceptable de celui-ci, présentant des taux de dissolution élevés d'amlodipine et de losartan même dans une condition de pH faible et une stabilité au stockage améliorée.

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