A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 31/445 (2006.01) C07D 211/32 (2006.01)
Patent
CA 2584547
The invention relates to a solid pharmaceutical composition comprising donepezil hydrochloride hydrate and a process for its preparation. In particular it relates to a composition and a process wherein the donepezil hydrochloride retains its polymorphic form and is therefore highly stable against conversion into other polymorphic forms.
La présente invention se rapporte à une composition pharmaceutique solide contenant du chlorhydrate hydrate de donépézil, et à son procédé de préparation. L'invention concerne en particulier une composition et un procédé dans lesquels le chlorhydrate de donépézil conserve sa forme polymorphe et est donc très stable vis-à-vis d'une conversion en d'autres formes polymorphes.
Kotar-Jordan Berta
Smrkolj Matej
Vrbinc Miha
Zupet Rok
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Krka Tovarna Zdravil D.d. Novo Mesto
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