Solid pharmaceutical compositions containing miltefosine for...

A - Human Necessities – 61 – K

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A61K 31/685 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2318260

The present invention relates to new solid pharmaceutical compositions containing hexadecylphosphocholine (miltefosine) for oral administration in the treatment of leishmaniasis, a process for the manufacture of said pharmaceutical composition, a dosage scheme for oral administration of said pharmaceutical composition in the treatment of leishmaniasis, and finally a combination comprising said solid pharmaceutical composition, an antiemeticum, and/or an antidiarrhoeal.

L'invention concerne de nouvelles compositions pharmaceutiques solides contenant hexadecylphosphocholine (miltefosine) et servant à traiter la leishmaniose par administration orale, un procédé servant à préparer ladite composition pharmaceutique, un plan de dosage servant à effectuer l'administration orale de ladite composition pharmaceutique afin de traiter la leishmaniose et, enfin, une combinaison contenant ladite composition pharmaceutique solide, un antiémétique et/ou un antidiarrhéique.

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