Solid pharmaceutical compositions containing pregabalin

Details Solid pharmaceutical compositions containing pregabalin Solid pharmaceutical compositions containing pregabalin

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 31/197 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2628200

A solid pharmaceutical composition containing pregabalin is described. The composition includes a matrix forming agent and a swelling agent and is suitable for once daily oral administration. Exemplary matrix forming agents include mixtures of polyvinyl acetate and polyvinylpyrrolidone, and exemplary swelling agents include cross-linked polymers of polyvinylpyrrolidone.

Cette invention concerne une composition pharmaceutique solide contenant de la prégabaline. Cette composition, qui comprend un agent formant une matrice et un agent gonflant, convient pour une administration orale journalière unique. Parmi les agents pouvant former des matrices, on peut citer des mélange d'acétate de polyvinyle et de polyvinylpyrrolidone, et comme agents gonflants des polymères réticulés de polyvinylpyrrolidone.

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