Solid pharmaceutical dosage forms having an extended...

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/42 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/13 (2006.01)

Patent

CA 2141691

The present invention provides solid pharmaceutical compositions in dosage form containing an active ingredient ar princ- iple, preferably memantine, which exhibit an extended two-phase release profile and which are characterized by the presence of both a water-soluble and a water-insoluble salt of casein, preferably sodium and calcium caseinate, in the matrix thereof, in broad proportions and in a total amount between 5 and 98% by weight of the composition, and with a process for the production there- of.

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