Solid-phase analytical device and method for using same

Details Solid-phase analytical device and method for using same Solid-phase analytical device and method for using same

G - Physics

01

N

167/44

G01N 33/546 (2006.01) G01N 31/22 (2006.01) G01N 33/52 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) G01N 33/576 (2006.01) G01N 33/76 (2006.01)

Patent

CA 1281642

Abstract of the Disclosure A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens or antibodies, is disclosed. The material comprises a porous matrix of fibers and a plurality of substantially spherical, solid particles having an average diameter of from about 0.1 to about 5 microns. The particles are retained and immobilized upon the fibers of the matrix. Preferably, the particles have on their surfaces a substance capable of reaction with the analyte in the sample, and the average diameter of the particles is less than the average pore size of the matrix. The device, in a preferred embodiment, comprises a substantially planar layer of the described material.

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