Solid-phase and solution-phase synthesis of...

Details Solid-phase and solution-phase synthesis of... Solid-phase and solution-phase synthesis of...

C - Chemistry, Metallurgy

07

H

C07H 3/06 (2006.01) C07H 15/207 (2006.01)

Patent

CA 2491555

One aspect of the present invention relates to solution-phase approaches to GPI synthesis. Another aspect of the present invention relates to key building blocks, and syntheses thereof, useful for GPI assembly. Yet another aspect of the invention relates to an automated method for the synthesis of GPIs and fragments thereof.

L'invention concerne des approches en phase soluble pour la synthèse du glycosylphosphatidylinositol (GPI). Selon un aspect de l'invention, on utilise des séquences clés de construction et leurs synthèses pour des ensembles GPI. Dans un autre aspect de l'invention, on utilise un procédé automatisé pour la synthèse desdits GPI et de leurs fragments.

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