Solid phase assay with one component immobilized on solid...

G - Physics – 01 – N

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167/44, 150/8

G01N 33/543 (2006.01) C12M 1/34 (2006.01) C12Q 1/00 (2006.01) G01N 33/53 (2006.01)

Patent

CA 1109791

ABSTRACT A method and apparatus for conducting chemical reactions at a liquid-solid interface wherein a reaction component is fixed on the surface of a solid phase immersed in a liquid phase containing a freely diffusing, mobile reaction component. The apparatus comprises a substantially smooth-surfaced matrix of appropriate geometrical configuration designed to provide a large surface to volume ratio, a short transfer distance from the mobile component to the fixed component distributed on the solid phase surface and to drain freely upon removal from the reaction liquid.

305110

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