C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 19/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12M 1/34 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2497297
The invention relates to methods for detection of nucleic acids on a solid phase, combining high affinity and high specificity. More particularly, the invention relates to methods combining high-affinity hybridization with highly specific enzymatic discrimination in solid phase based nucleic acid assays. This invention further relates to kits containing the reagents necessary for carrying out the disclosed assays.
L'invention concerne des procédés de détection d'acides nucléiques sur une phase solide, combinant une haute affinité avec une haute spécificité. Plus particulièrement, l'invention concerne des procédés combinant une hybridation haute affinité avec une discrimination enzymatique hautement spécifique dans des dosages d'acide nucléique en rapport avec une phase solide. L'invention concerne également des kits contenant les réactifs nécessaires à la mise en oeuvre des dosages précités.
Burmeister Jens
Diessel Edgar
Dorn Ingmar
Quinn Jack
Warner Brian
Bayer Healthcare Llc
Torys Llp
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