Solid phase matrices and a process for the production thereof

Details Solid phase matrices and a process for the production thereof Solid phase matrices and a process for the production thereof

C - Chemistry, Metallurgy

07

K

530/17, 167/44,

C07K 17/00 (2006.01) G01N 33/531 (2006.01) G01N 33/543 (2006.01)

Patent

CA 1335265

A solid phase matrix comprises an insoluble carrier material to which is bound a protein with a molecular weight of above about 200,000 which has a plurality of components P1 of a specific binding pair and the protein is cross-linked with a polymer of a plurality of the other component P2 of the specific binding pair, the polymer having not only binding points for P1 but also for an immunological complex to be determined; the matrix is useful in determining an analyte in a sample, for example, in an immunoassay; a process for producing the matrix comprises binding the protein to the insoluble carrier and cross-linking with the polymer via a specific binding of P1 with P2.

592220

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