Solid phase reagent and assay method for antibody using the...

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G01N 33/564 (2006.01) G01N 33/543 (2006.01) G01N 33/545 (2006.01) G01N 33/68 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2107557

By using a solid phase reagent comprising a carrier having the surface onto which functional groups containing a negative charge or a lone pair and/or free radicals containing a negative charge or a lone pair have been introduced and having .beta.2-glycoprotein I coated on the surface, antibodies specific to antiphospholipid syndrome can be specifically assayed. Antibodies specific to antiphospholipid syndrome can be assayed differentially from antibodies specific to infectious diseases by using the solid phase reagent described above or a further modified solid phase reagent.

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