Solid phase synthesis of acth

Details Solid phase synthesis of acth Solid phase synthesis of acth

C - Chemistry, Metallurgy

08

H

402/573, 530/17.

C08H 1/00 (2006.01) C07K 1/04 (2006.01) C07K 14/695 (2006.01) C08F 8/30 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1062249

ABSTRACT OF THE DISCLOSURE Resin peptides useful in the preparation of peptites having biological activity, and particularly such resin peptides containing ?-CH2-Phe-Glu at one end of an amino acid chain, ? being the resin and Phe and Glu being the residues of the amino acids phenylalanine and glutamic acid; and processes for the preparation of such resin peptides. Resin peptides are disclosed which contain amino acid chains identical with the amino acid chains of natural peptides having biological activity. Other resin peptides are disclosed which contain amino acid chains in which the amino acid residues differ in kind and sequence from amino acid chains of natural biologi- cally active peptites but from which peptides having bio- logical activity may be derived.

219789

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