Solid phase synthesis of protected peptides

Details Solid phase synthesis of protected peptides Solid phase synthesis of protected peptides

C - Chemistry, Metallurgy

07

C

260/468.8, 260/5

C07C 205/58 (2006.01) C07K 1/04 (2006.01) C07K 7/23 (2006.01)

Patent

CA 1085868

ABSTRACT OF THE DISCLOSURE The invention is addressed to the preparation of 3-nitro-4-bromomethyl benzoic acid, as a new compound from which 3-nitro-4-bromomethyl benzoyl amide polystyrene resin can be prepared for solid synthesis of protected peptide acids and amides and separation thereof without cleavage of acid labile protecting group or decomposition of aromatic acid groups and from which purified polypeptides can be formed.

251172

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