Solid phase system for use in ligand-receptor assays

Details Solid phase system for use in ligand-receptor assays Solid phase system for use in ligand-receptor assays

G - Physics

01

N

167/44, 150/9, 1

G01N 33/549 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/544 (2006.01) G01N 33/545 (2006.01) G01N 33/551 (2006.01) G01N 33/569 (2006.01) G01N 33/573 (2006.01) G01N 33/576 (2006.01) G01N 33/74 (2006.01)

Patent

CA 1272127

ABSTRACT OF THE DISCLOSURE Disclosed herein is a solid phase system for use in ligand-receptor assays, particularly immunoassays, for the detection of a selected analyte in a fluid sample. The system comprises a porous matrix in which entrapped are microspheres bound with a receptor capable of capturing a target ligand. Also disclosed is an apparatus for use in the ligand-receptor assays comprising a porous member which comprises such a solid phase system and a means for facilitating the flow of the fluid sample and liquid ligands used in the assay. Further disclosed is a ligand-receptor assay process using such a solid phase system. The method is particularly useful in assays of a virus, bacterium, fungus, parasite and other physiological marker.

505788

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