Solid preparation

Details Solid preparation Solid preparation

A - Human Necessities

61

K

A61K 9/24 (2006.01)

Patent

CA 2677201

A solid preparation containing compound (I), wherein the definition of compound (I) is as defined in the description, and pioglitazone, which is useful as a therapeutic drug for diabetes and the like and superior in the dissolution property, chemical stability and dissolution stability, is provided. A solid preparation containing the following first and second parts: (1) the first part containing compound (I) or a salt thereof and, as the first excipient, sugar or sugar alcohol; and (2) the second part containing pioglitazone or a salt thereof and, as the second excipient, sugar or sugar alcohol.

L'invention porte sur une préparation solide contenant un composé (I), dont la définition est donnée dans la description, et de la pioglitazone, qui est utile comme médicament thérapeutique pour le diabète et similaires et présente des propriétés supérieures de dissolution, de stabilité chimique et de stabilité de dissolution. L'invention porte également sur une préparation solide contenant les première et seconde parties suivantes : (1) la première partie contenant le composé (I) ou un sel de celui-ci et, comme premier excipient, du sucre ou un alcool de sucre ; et (2) une seconde partie contenant de la pioglitazone ou un sel de celle-ci et, comme second excipient, du sucre ou un alcool de sucre.

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