Solid preparation containing an insulin sensitizer

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/20 (2006.01) A61K 9/50 (2006.01) A61K 31/366 (2006.01) A61K 31/4439 (2006.01) A61K 31/64 (2006.01)

Patent

CA 2633149

The present invention intends to provide a solid preparation which contains an insulin sensitizer and an active ingredient other than an insulin sensitizer, and exhibits dissolution behavior of an insulin sensitizer similar to that of an insulin sensitizer from "a solid preparation containing only an insulin sensitizer as an active ingredient". The solid preparation comprises "a part containing coated particles in which the particles containing an insulin sensitizer are coated with lactose or a sugar alcohol" and "a part containing an active ingredient other than an insulin sensitizer".

La présente invention concerne une préparation solide qui contient un sensibilisateur à l'insuline et un principe actif autre qu'un sensibilisateur à l'insuline, et présentant un comportement de dissolution d'un sensibilisateur à l'insuline analogue à celui d'un sensibilisateur à l'insuline dérivé d'une ''préparation solide contenant uniquement un sensibilisateur à l'insuline en tant que principe actif''. La préparation solide comporte '' une partie contenant des particules enrobées, les particules enrobées contenant un sensibilisateur à l'insuline étant enrobées avec du lactose ou d'alcool de sucre'' et une partie contenant un principe actif autre qu'un sensibilisateur à l'insuline''.

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