Solid products with improved stability and method for...

A - Human Necessities – 61 – K

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Details

A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/28 (2006.01) A61K 47/02 (2006.01) A61K 47/36 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2563271

A solid pharmaceutical preparation excellent in storage stability including light stability and a process for producing the solid pharmaceutical preparation. The solid pharmaceutical preparation is characterized by comprising: a raw pharmaceutical preparation comprising a core part containing an active ingredient and a core-coating layer with which the core part is coated and which comprises a dusting powder; and a coating film with which the raw pharmaceutical preparation is coated and which contains a compound having photocatalytic activity or semiconducting properties. The process for producing the solid pharmaceutical preparation is characterized by comprising a step in which a core part containing an active ingredient is coated by the powder coating method with ingredients for constituting a core-coating layer containing a dusting powder.

Préparation pharmaceutique solide d'excellente stabilité au stockage avec photostabilité et un procédé de production de la préparation pharmaceutique solide. La préparation pharmaceutique solide est caractérisée par : une préparation pharmaceutique brute qui comprend un noyau contenant un ingrédient actif et une couche qui recouvre le noyau et qui comprend une poudre de poussière ; une couche d'enrobage qui recouvre la préparation pharmaceutique brute et qui contient un composé à l'activité photocatalytique ou des propriétés semi-conductrices. Le procédé de production de la préparation pharmaceutique solide est caractérisé par une étape au cours de laquelle un noyau contenant un ingrédient actif est recouvert par la méthode de revêtement en poudre avec les ingrédients nécessaires à la constitution d'une couche recouvrant le noyau et contenant une poudre de poussière.

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